Expression and roles of glutamate (NMDA) receptors on T cell subsets

Expression and roles of glutamate (NMDA) receptors on T cell subsets

Rationale Tryptophan is an essential amino acid and its oxidative catabolism, through the action of its rate-limiting enzyme, indoleamine 2,3 dioxygenase (IDO), generates functional molecules in neurons. We studied the function of the tryptophan catabolism pathway on immune regulation. We have shown previously that human eosinophils constitutively express bioactive IDO and that co-culture of eo...

Asymmetric Involvement of Central and the Peripheral NMDA Glutamate Receptors in the Expression of Withdrawal Syndrome in Morphine-Dependent Mice

Introduction: Morphine withdrawal syndrome is mediated via several central and peripheral neurological pathways. In the present study we investigated the role of N-methyl-D aspartic acid (NMDA) glutamate receptor on naloxone-induced withdrawal syndrome in morphine-conditioned mice. Materials and Methods: We designed two separate experiments. In experiment one, 30 male NMRI mice were divide...

The Immunomodulatory Effect of Cyclophosphamide on Regulation of T-Cell Subsets and Antigen Presenting Cells.

asymmetric involvement of central and the peripheral nmda glutamate receptors in the expression of withdrawal syndrome in morphine-dependent mice

introduction: morphine withdrawal syndrome is mediated via several central and peripheral neurological pathways. in the present study we investigated the role of n-methyl-d aspartic acid (nmda) glutamate receptor on naloxone-induced withdrawal syndrome in morphine-conditioned mice. materials and methods: we designed two separate experiments. in experiment one, 30 male nmri mice were divided int...

P76: The Neuroprotective Roles of NMDA Receptors Antagonist Against with Lesion in Central Nucleus of Amygdala

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